Heat-Labile Enterotoxin-Induced PERK-CHOP Pathway Activation Causes Intestinal Epithelial Cell Apoptosis
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منابع مشابه
Heat-Labile Enterotoxin-Induced PERK-CHOP Pathway Activation Causes Intestinal Epithelial Cell Apoptosis
Enterotoxigenic Escherichia coli (ETEC) is a leading cause of diarrhea among children and travelers in developing countries, and heat-labile enterotoxin (LT) is one of the most important virulence factors. The pathogenesis of and virulence factors associated with ETEC have been well-characterized; however, the extent to which ETEC damages host cells remains unclear. In this study, we found that...
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9 Running title: Surface binding mutants of LT 10 11 12 Benjamin Mudrak 1 , Daniel L. Rodriguez 2 , and Meta J. Kuehn 1,2* 13 Departments of Molecular Genetics and Microbiology 1 and Biochemistry 2 14 Duke University Medical Center, Durham, NC 27710 15 16 17 18 19 20 21 * To whom correspondence should be addressed: Tel. 919-684-2545; Fax 919-684-8885; 22 E-mail: [email protected] 23 Copyr...
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ژورنال
عنوان ژورنال: Frontiers in Cellular and Infection Microbiology
سال: 2017
ISSN: 2235-2988
DOI: 10.3389/fcimb.2017.00244